Cleaning your water system regularly is the best way to prevent water-borne illnesses such as Giardia, Ecoli, infectious hepatitis and all sorts of microbes. If you're camping in areas where the water is spring or well fed you may not be aware there's a problem with the water until it's too late and you're sick.
It's not just virus and bacteria you need to worry about. Illnesses such as Giardia are caused by cysts that aren't easily filtered out with common household water filters.
Many campgrounds use water from their own wells - and what problems they have will be passed onto to you. Since water-borne illnesses tend to affect the very young or the very old, if you're traveling with children, or are a senior, or have health issues, it's even more important to make sure your fresh water tank is truly fresh!
If you are traveling with very young children or are a senior or have health issues, use a water filtering system on your kitchen faucet, or a water-filtering pitcher (such as a Pur filtering pitcher), or bottled water for drinking.
Your fresh water system is simply a large tank inside the RV that you fill with fresh water. Contamination can come in through the portal where you fill the tank if you leave it open, use a dirty hose; have a dirty faucet at the campground or facility where you're filling up, or if the water itself is contaminated for some reason. Add the fact that your RV tank is exposed to heat, air and sloshing water that soon dissipates any chlorine in the system rapidly and you're looking at some really iffy water safety. If there is any oil, slime, dirt or algae in the tank from prior use or poor cleaning, your chances of drinking pure water diminish even more.
A healthy human body is very good at fending off most of the bacteria and microscopic contaminants that are found in water everywhere - even at home in our own city water supplies. What happens with an RV system is that that water sits in the tank where heat, and sometimes light, can help those bacteria reproduce over time - especially if the water sits for a month or more. If water is circulating, being used and replaced on a regular basis, that bacterial growth is less likely to occur. Cleaning your system regularly helps sanitize the inside of the tanks and keeps bacterial growth down.
There are several times you should clean your water system:
Once clean your tank is ready for traveling! At this point, the Environmental Protection Agency (EPA) advocates using a method called "Super-chlorination / de- chlorination" to prevent bacterial growth while you're traveling. To do this chlorine is added to the water in increased amounts to provide a minimum chlorine residual of 3.0 ppm (parts per million) for a contact period of five minutes. You now have a reservoir full of water with a high concentration of chlorine. It's safe from a bacterial explosion, but it's definitely not what you want to use for making a cup of tea. You need to de-chlorinate it first using a ceramic RV water filter. Check with your RV dealer for recommendations of a product to suit your needs.